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HDL Balance


  • Supports Healthy Blood Lipid Levels
  • TCM: Supports Healthy Digestion, Blood Circulation, Spleen/Stomach Health

HDL Balance is developed by fermenting Monascus purpureus (red yeast) on commercially grown rice. The resulting fermented product contains at least nine naturally occurring compounds called monacolins. The rice and yeast are then ground into a red powder. This formula is citrinin-free.[1]

Fueled by extensive studies, scientific evidence demonstrating the safety, tolerability, and efficacy of red yeast rice (RYR) continues to mount.[2-6,12] The first use of RYR was documented in 800 A.D., during the Tang Dynasty. Subsequently, during the Ming Dynasty (1368-1644), the manufacturing process was published in the ancient Chinese pharmacopoeia. The typical Asian diet contains 14-55 grams of naturally occurring RYR per day.[7]

The potential benefits of consuming RYR or its supplement form, RYRE (red yeast rice extract), are multi-faceted. In traditional Chinese medicine, the powdered form is called Hong Qu, Hong Mi, or Chi Qu. Considered sweet, acidic, and warm, it is used to strengthen the spleen and stomach, thereby promoting digestion, invigorating blood circulation, and eliminating blood stasis.[8] In western medicine, RYR has been shown to down-regulate adipogenic transcription factors such as PPAR gamma and other genes that differentiate adipocytes.[9]

Researchers believe the most active constituents of RYR are its various monacolins, particularly monacolin K, which the body converts to ß-hydroxy acid. A study utilizing hamsters concluded that “the activity of RYR is, at least, partially mediated by enhancement of acidic sterol excretion.”[10] RYR also contains various pigments, tannins, phytochemicals such as sterols and isoflavones, and mono-unsaturated fatty acids, all of which may work synergistically with the monacolins.[4,8]

Since 1996, there have been no fewer than nine randomized, controlled RYR/RYRE trials, involving thousands of subjects. Studies since the 1970s have demonstrated that RYRE provides healthy lipid level support. The medical literature associated with these studies includes comparative, case series, and dosing studies.[2-12]

In its natural state, RYRE may contain the mycotoxin, citrinin, a secondary metabolite of the monascus species. [3] Accordingly, Lifestyle Research carefully tests and documents each and every batch of RYRE raw material to comply with strict limits for citrinin (in ppb) and to assure its safety. Repeated analysis has found Lifestyle Research’s HDL Balance to be so well within the limits of safety that it earns the designation, “citrinin-free.”[1]

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